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Rossignol DA, Frye RE (2012) A review of research trends in physiological abnormalities in autism spectrum disorders: immune dysregulation, inflammation, oxidative stress, mitochondrial dysfunction and environmental toxicant exposures

Younger patients often have better outcomes with both treatments, but stem cell therapy may be particularly effective for those under 60

Early-stage greying caused by nutritional deficiencies, stress, or inflammation may be partially reversible

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Consequently, conditions that promote phagocyte proliferation, such as the inflammatory response, lead to the production of substantial amounts of ROS via NOX